A 46-year-old woman suffering from cholelithiasis developed jaundice. Her urine became dark yellow, while feces are light-colored. What substance will be the most increased in concentration in the blood serum in this case?

Answer options

1. Unconjugated bilirubin
2. Urobilinogen
3. Mesobilirubin
4. Biliverdine
5. Conjugated bilirubin

Explanation

Conjugated hyperbilirubinemia occurs in several disorders associated with bile duct obstruction, with subsequent obstruction of biliary flow in this case due to bile stone (cholelithiasis).