Blood of the patients with diabetes mellitus shows increased content of free fatty acids. Name the most likely cause of this:

Answer options

1. Activation of apo?1, apo?2, and apo?4 apolipoprotein synthesis
2. Accumulation of palmitoyl-CoA in cytosol
3. Activation of ketone bodies utilization
4. Decreased activity of plasma phosphatidylcholine-cholesterol-acyltransferase
5. Increased activity of adipose triglyceride lipase

Explanation

Adipose triglyceride lipase (ATGL) is a triacylglycerol hydrolase that promotes the catabolism of stored fat.