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Exam questionKROK 1Medicine ยท 2017

T-lymphocytes are determined to be affected with HIV. In this case viral enzyme reverse transcriptase (RNA-dependent DNA-polymerase) catalyzes the synthesis of:

Answer options

  1. Viral DNA based on the DNA matrix
  2. Informational RNA based on the viral protein matrix
  3. Viral protein based on the viral RNA matrix
  4. Viral RNA based on the DNA matrix
  5. DNA based on the viral RNA matrix
Correct answer

DNA based on the viral RNA matrix

Explanation

Reverse transcriptase catalyzes the formation of double-stranded deoxyribonucleic acid (DNA) from a single-stranded ribonucleic acid (RNA) genome. It is called "reverse" transcriptase because it reverses the usual direction of information flow, from DNA to RNA. Reverse transcriptase is characteristic of retroviruses, including HIV (human immunodeficiency virus), the virus responsible for AIDS (acquired immunodeficiency syndrome).

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