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Exam questionKROK 1Medicine ยท 2017

Therapeutics unit of a hospital received a man suffering from ulcer disease of the stomach with hyperacidity. Which of the listed group of drugs must be used as a part of the complex therapy of this patient?

Answer options

  1. Histamine Hi-receptor antagonists
  2. Calcium channel blockers
  3. Histamine H2-receptor antagonists
  4. Nonsteroidal antiinflammatory drugs
  5. Steroidal antiinflammatory drugs
Correct answer

Histamine H2-receptor antagonists

Explanation

Histamine H2 -receptor antagonists' exampleCimetidine, ranitidine, Famotidine, nizatidineReversible block of histamine H2 receptors in the stomach. Leads to decreased acid secretion by parietal cells.Histamine-2 (H2) antagonists are used in the management of dyspepsia, for example, gastritis and gastroesophageal reflux disease. There are nowadays used the second line to the more effective proton pump inhibitors. Examples include:

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