A patient, who has been subsisting exclusively on polished rice, has developed polyneuritis due to thiamine deficiency. What substance is an indicator of such avitaminosis, when it is excreted with urine?

Answer options

1. Pyruvic acid
2. Uric acid
3. Malate
4. Phenyl pyruvate
5. Methylmalonic acid

Explanation

A patient, who has been subsisting exclusively on polished rice, has developed polyneuritis due to thiamine deficiency. What substance is an indicator of such avitaminosis, when it is excreted with urine?Vitamin B1 Deficiency and Beri. Primary vitamin B1 (thiamine) deficiency is caused by a lack of vitamin B1 in the diet and is often seen in countries where the main diet is polished rice (white rice with the outer layers removed) The excretion of pyruvic acid in urine increases in thiamine deficiency and in beriberi.