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Exam questionKROK 1Medicine ยท 2017

A patient complaining of heartburn has undergone biopsy of the gastric mucosa. In the sample there are numerous cells with oxyphilic cytoplasm in the glandular epithelium. Name these cells:

Answer options

  1. Exocrine parietal cells
  2. Exocrine chief cells
  3. Mucous cells
  4. Endocrine cells
  5. Epithelial cells
Correct answer

Exocrine parietal cells

Explanation

A patient complaining of heartburn has undergone biopsy of the gastric mucosa. In the sample there are numerous cells with oxyphilic cytoplasm in the glandular epithelium. Name these cells:Parietal cells are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are in the gastric glands found in the lining of the fundus and in the body of the stomach. The best-known component of gastric juice is hydrochloric acid, the secretory product of the parietal, or oxyntic cell. It is known that the capacity of the stomach to secrete HCl is almost linearly related to parietal cell numbers too much parietal cell lead to high HCL that causes ulcer (Heartburn) is a painful burning feeling in your chest or throat. It happens when stomach acid backs up into your esophagus.

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