Streptomycin and other aminoglycosides prevent the joining of formyl-methionyl-tRNA by bonding with the 30S ribosomal subunit. This effect leads to disruption of the following process:

Answer options

1. Translation initiation in procaryotes
2. Transcription initiation in eucaryotes
3. Replication initiation in procaryotes
4. Translation initiation in eucaryotes
5. Transcription initiation in procaryotes

Explanation

N-formyl-methionyl-tRNA (tRNAfMet) is the aminoacyl-tRNA that initiates bacterial protein synthesis aminoglycosides are known to target rRNA in prokaryotes prevent the joining of formyl methionyl tRNA by bonding with the 30S ribosomal subunit and thereby alter protein translation.