An infant, who was on synthetic formula feeding, developed signs of vitamin B1 deficiency. What reactions does this vitamin take part in?

Answer options

1. Amino acids decarboxylation
2. Amino acids transamination
3. Redox reactions
4. Proline hydroxylation
5. Keto acids oxidative decarboxylation

Explanation

Vitamin B1, as the coenzyme thiamin pyrophosphate, is involved in the oxidative decarboxylation of α-ketoacids, and functions in transketolase reactions. Thiamin is critical for decarboxylation of pyruvate in preparation for entry into the tricarboxylic acid cycle.