A 30-year-old person has been stung by a bee. The stung area exhibits edema, hyperemia, and elevated temperature. What is the initial pathogenetic factor of inflammatory edema in this case?

Answer options

1. Increase of microvascular permeability
2. Disturbed lymphatic efflux
3. Decrease of oncotic blood pressure
4. Increase of osmotic pressure in the inflammation focus
5. Increase of capillary blood pressure