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Exam questionKROK 1Medicine ยท 2020

Autopsy of the body of a 40-year-old patient detected groups of enlarged follicles in the small intestine. Their surface has ridges and fissures arranged in a pattern that resembles gyri and sulci of the brain. The follicles protrude above the surface of the intestinal mucosa. On section they are gray red and juicy. Microscopy shows proliferation of monocytes, histiocytes and reticular cells, there are macrophage clusters that form granulomas, while lymphocytes are depleted. What disease can be characterized by these changes?

Answer options

  1. Cholera
  2. Typhoid fever
  3. Amebiasis
  4. Salmonellosis
  5. Dysentery
Correct answer

Typhoid fever

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