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Exam questionKROK 1Medicine ยท 2020

Autopsy of the body of 6 month old child, who died of sepsis, revealed the absence of thymus and diminished size and weight of the spleen. Microscopy of the spleen detected the absence of periarterial T dependent zones of the follicles and red pulp depletion; In the lymph nodes there is no paracortical zone that is represented mainly by T lymphocytes. B zones in the peripheral immune organs are developed normally. What pathological process is it?

Answer options

  1. Accidental thymic involution
  2. HIV infection
  3. Glanzmann-Riniker syndrome (Cellular and humoral immune deficiency)
  4. DiGeorge syndrome (Cellular immune deficiency)
  5. Brunton syndrome (humoral immune deficiency)
Correct answer

DiGeorge syndrome (Cellular immune deficiency)

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