A patient with chronic glomerula nephritis has dem Kood pressure of 210/100 mm Hg Seart rate or s/min and expanded burder of the heart. What is the main mechanism of arterial hypertension development

Answer options

1. Activation of renin-angiotensin- aldosterone system
2. Increased activity of sympathetic nervous system
3. Increased vasopressin production
4. Increased volume of circulating blood
5. Hyperfunction of the heart