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Exam questionKROK 1Medicine · 2020

A 56-year-old man presents for a checkup. The patient says he has to urinate quite frequently, but denies any dysuria or pain on urination. Past medical history is significant for diabetes mellitus type 2 and hypertension, both managed medically. Current medications are metformin, aspirin, rosuvastatin, captopril and furosemide. Laboratory findings are significant for the following: Glycated Hemoglobin (Hb A1c) - 8.0%, Fasting Blood Glucose - 12 mmol/L. His doctor decides to add glibenclamide to the therapy. Which of the following is the most likely mechanism of this drug’s action?

Answer options

  1. Stimulation of glucose reuptake by the cell
  2. -
  3. Stimulation of insulin release
  4. Facilitation of glucose absorption in the intestine
  5. Inhibition of insulin release
Correct answer

Stimulation of insulin release

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