A man presents with fatigue and joint pain in his fingers and wrists for thc last 2 months. The pain is present in both hands and the wrists are swollen. Furthermore, he describes morning stillness in his joints lasting about 2 hours, which improves with use. His past medical history reveals he has been successfully treated for H. pylori related ulcers last year. Ile denies smoking and stopped drinking when his gastric symptoms started. much or the following drugs is the best choice for his joint pain management?