Exam questionKROK 1Medicine ยท 2020
A researcher is investigating the relationship between inflammatory mediators. He performs an experiment, investigating the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on patients with high-grade fever. HIS research indicates that certain NSAIDs act as competitively reversible inhibitors of the cyclooxygenase (COX) enzymes. It is known that COX catalyzes the formation of prostaglandins from a certain molecule that itself is derived from the cellular phospholipid bilayer by phospholipase A2. Which of the following molecules is a precursor of an inflammatory mediators mentioned above?
Answer options
- Tyrosine
- Cholesterol
- Palmitic acid
- Proopiomelanocortin
- Arachidonic acid
Correct answer
Arachidonic acid
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