Diagnostics of hepatitis and myocardial infarction shows that the activity of alanine and aspartate amino-transferases sharply increases in blood plasma in such cases. What causes these biochemical changes in the blood?

Answer options

1. Increased rate ofamino acid synthesis
2. Damage to cell membranes and release of enzymes into the blood
3. Increased rate ofamino acid breakdown
4. Pyridoxine deficiency
5. Increased activity of enzymes due to the effect of hormones