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Exam questionKROK 1Medicine ยท 2022

A 47-year-old man was diagnosed with arthritis of the toe on his right foot and nephrolithiasis consisting of uric acid. The patient is taking allopurinol. What biochemical defect has likely been detected in this patient?

Answer options

  1. Increased leukotriene levels
  2. Disturbed purine metabolism
  3. Disturbed arachidonic acid metabolism
  4. Disturbed pyrimidine metabolism
  5. Urea synthesis defect
Correct answer

Disturbed purine metabolism

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