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KROK 1 Pharmacy 2009 Questions | KROKEXAM

Browse 2009 KROK 1 Pharmacy exam questions with answers and explanations.

Exam questions

200 Questions
1

Microscopical examination of primary cortex of a root in its absorption zone revealed that it consisted mainly of multilayer living loose parenchyma with amyloid granules. It is called:

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2

A patient has been administered a competitive inhibitor of cholinesterase. Name it:

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3

A 30 year-old patient suffering from pulmonary tuberculosis, has been prescribed isoniazid. Continuous taking of this drug may lead to the deficiency of the following vitamin:

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4

Active form of one of the sulphurcontaining amino acids can be used as a methyl group donor for the drug methylation. Specify this amino acid:

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5

A chemist in analytical laboratory needs to standardize solution of sodium hydroxide. What primary standard solution can be applied for this purpose?

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6

A patient has taken a large dose of a barbiturate hypnotic (amytal) that inhibits NAD-dependent dehydrogenase of the respiratory chain. What process running in the mitochondria will be disturbed?

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7

Particles of dispersed phase of an emulsion are deformed and look as polyhedrons. What emulsion is it?

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8

A drug which inhibits ATP synthesis in a cell has been used during an experiment. What type of transmembrane transport will be disturbed?

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9

Increase in secretion of hydrochloric acid in the stomach of an experimental animal can be provoked by subcutaneous injection of the following gastrointestinal hormone:

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10

Protein digestion in the stomach is carried out by pepsin secreted in form of an inactive pepsinogen. Pepsinogen is converted to pepsin by the removal of the N-terminal peptide that is provoked by:

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11

In order to keep eubiotics viable and stable, frozen microorganisms are dried out under the conditions of high vacuum. This method is called:

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12

Cardiac diseases are treated with cocarboxylase preparation. This preparation is the coenzymatic form of the following vitamin:

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13

During starvation the normal rate of glucose in blood is sustained due to the gluconeogenesis stimulation. Which of the following substances can be used as a source for glucose synthesis?

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14

It is known that infectious type B hepatitis is a systemic disease caused by the type B hepatitis virus and characterized by a predominant liver affection. Choose from the below given list the drugs for the etiotropic therapy of this infection:

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15

Choose a non-salt-forming oxide from the following compounds:

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16

What substance can act as both oxidant and reducer in oxidation-reduction reactions?

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17

Oxidative deamination of biogenic amines in the tissues is catalyzed by the following enzyme:

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18

Nitrogen (I) oxide (N2O) is applied for inhalation narcosis. It is obtained by heating of:

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19

Quantitative determination of pharmaceutical substances can be done by means of acidimetry. Its titrant is the secondary standard solution of hydrochloric acid. According to which compound the precise concentration of hydrochloric acid can be determined?

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20

Analysis of a patient’s urine revealed increased concentration of the uric acid. The patient was prescribed allopurinol. What is the biochemical mechanism of its action?

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21

Physical exercise results in an increase in thermogenesis due to an increase in heat production in the following structure:

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22

Plant pathogenic microorganisms relate to various groups. Which of them causes diseases of medicinal plants most often?

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23

It is known that proteins, fats and carbohydrates are digested by means of proteases, lipases and amylases, respectively. Which of digestive juices contains all these groups of enzymes enough for digestion?

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24

Colloidal protection is used while manufacturing drug preparations. Name the preparation of colloidal silver protected by proteins:

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25

It is known that the unconjugated bilirubin being the product of heme catabolism is detoxicated in liver. Which compound is involved into the bilirubin detoxication within the hepatocytes?

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26

An adult presents with systemic arterial pressure at the rate of 160/100 mm Hg. This might be caused by the increased concentration of the following hormone in blood:

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27

It is required to diminish pump function of patient’s heart. This can be done by means of blockers of the following membrane cytoreceptors:

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28

Taking vasopressin resulted in a decrease in diuresis. The reason for it is increased water reabsorption in the following renal tubuli:

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29

Under conditions of high exterior temperature a ventilating fan can relieve staying in the premises because it intesifies heat emission by means of:

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30

In the pharmaceutical production processes of drug synthesis take place under different conditions. Entropy stays unchanged in the following process:

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31

Specify the complexing agent for a complex compound K2[HgI4]:

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32

Analysis of a patient’s urine showed an increase in Na+ ions concentration and a decrease is K+ ions concentration. This might be caused by the reduced secretion of the following hormone:

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33

Choose a reagent for synthesis of acetic acid hydrazide from ethyl acetate: {# "img":"sv4jfqeo6pova0o5chkh9uhsn.png", "alt":"Option","whb":"195:82:" #}

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34

When computing quantities of adjuvant substances required to make liquid drug forms isotonic, the values of isotonic quotients are used. What is the quotient for zinc sulphate if known that it dissociates completely in an aqueous solution?

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35

After a stomach resection a patient presented with weakness, skin pallor, face puffiness, enlargement of liver and spleen. Analysis of the peripheral blood revealed megaloblasts and megalocytes; hyperchromatism (colour index - 1,3). What type of anaemia is observed in this patient?

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36

Water-soluble vitamins take coenzyme form in an organism. Thiamine diphosphate is coenzyme of the following vitamin:

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37

Quantitative determination of calcium chloride is carried out by method of direct chelatometric titration. Choose an indicator for fixation of the titration endpoint:

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38

One of the examined soft fruits is characterized by essential-oil exocarp, spongioid mesocarp and overgrown endocarp that consists of juice saccules. What fruit was under examination?

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39

Enzymes (biological catalysts) are used as pharmacologic preparations. What is the mechanism of enzyme action in the biochemical reactions?

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40

After a solution had been heated with (NH4)2S2O8 in presence of AgNO3, it turned crimson. What ions were present in the solution?

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