KROK 1 Pharmacy 2010 Questions | KROKEXAM
Browse 2010 KROK 1 Pharmacy exam questions with answers and explanations.
Exam questions
200 QuestionsDecarboxylation of the amino acid histidine results in formation of histamine in the cells. Neutralization of this biogenic amine takes place due to the following enzyme:
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Chlorophyll, the green pigment of plants, is a chelate compound. Specify the chelating ion in the chlorophyll:
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A flower has the androecium consisting of two long and two short stamens. Therefore the flower’s androecium is:
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Potassium dichromate K2Cr2O7 is applied as oxidant in acidic medium. What is the product of reduction of dichromateion Cr2O2−7 under these conditions?
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In course of an experiment a dog has been injected a preparation that reduces secretory and motor activity of stomach. What preparation is it?
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What ion mechanism is responsible for the development of depolarization phase of action potential?
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Study of an isolated heart shows that it keeps on contracting even after removal from the body. This effect owes to the following peculiarity of the myocardium:
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What product is obtained in Wagner reaction during oxidation of alkenes with potassium permanganate in the aqueous medium?
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Study of the antibioticogram of the pure salmonella culture revealed multiple antibiotic resistance. What factor might have caused this effect?
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After a 5-year-old child has been brought home from the kindergarten he presented with weakness, headache, body temperature rise up to 37, 5oC. What period of disease develompent is the case?
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It is required to determine the amount of sodium salicylate in a solution. What titrimetric method can be applied for the quantitative determination of aromatic compounds?
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When copper (II) hydroxide enters into reaction with alkali, complex compounds are produced. What is the coordination number of copper in such compounds?
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Interaction of aniline with excess of bromine water resulted in formation of white precipitate. What substance was produced?
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For treatment of the psychosis a patient was administered the neuroleptic aminazine. The main way of its biotransformation in the organism is induction of microsomal oxidation. Speci- fy the principal component of this system:
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Every year during the plant blossomi- ng a female patient develops acute catarrhal inflammation of conjunctiva and nasal mucosa that is the clinical presentation of an allergy. These symptoms relate to the following type of allergic reactions:
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A patient is suspected to have the typhoid fever. What method of laboratory diagnostics would be the most appropriate for confirmation of this diagnosis in the first week of disease?
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Inoculation of hen’s embryos is the main method of detection of influenza virus. In order to neutralize associated bacterial flora in the material under examination (nasopharyngeal lavage) it is necessary to add beforehand:
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Choose the initial compound for one-stage synthesis of phthalic acid:
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Interaction of lactic acid with SOCl2 excess will result in production of the following compound: {# "img":"lczxglky2142r1xly8nw3xe73.png", "alt":"Option","whb":"311:93:" #}
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A group of alpinists climbing to the top had their blood tested. The test revealed erythrocytosis and increase in hemoglobin rate. What type of hypoxia caused the stimulation of erythropoiesis in the bone marrow?
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A 42-year-old patient suffering from chronic calculous cholecystitis complains of acute pain in the right subcostal area, itching and skin icteritiousness, multiple petechial haemorrhages, saponified and light-coloured feces (steatorrhea). What type of icterus is it?
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Microscopic examination of leaf serration revealed secretory structures secreting some liquid. What are these structures called?
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In pharmaceutical synthesis both simple and complex reactions are applied. Specify the order of the simple reaction of type 2A + B = 3D:
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Choose a reduction-oxidation method for the quantitative determination of iron (II) salts in a solution that contains hydrochloric acid:
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In order to prevent adipose degeneration of liver after the viral hepatitis a patient should be administered lipotropins. Name one of them:
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Pharmaceutical practice widely applies isotonic solution of sodium chloride. How much sodium chloride is to be takenin order to prepare 100 g of the isotonic solution?
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Which element has the same valence in both hydrogen compound and higher oxide?
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Toluol is converted to the benzoic acid under the following conditions: {# "img":"x3e7op3eh6dltsbe4iub7w6y2.png", "alt":"Option","whb":"250:138:" #}
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Some drugs are colloid solutions. Colloidal disperse systems are the systems whose particles are sized within the range of:
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The thyroid gland synthesizes a hormone that lowers the rate of Ca2+ concentration in blood thus facilitating its deposition in bones. What hormone is it?
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Which of the following compounds forms a propionic aldehyde as a result of alkaline hydrolysis (H2O, OH−)?
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In order to choose an indicator during the acid-bace titration a titration curve is made which is the dependence of:
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Nephron is the structural and functional unit of the kidneys. The process of filtration takes place in the following part of it:
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Inflammatory processes in the gall bladder exert negative influence on the colloidal properties of bile. This may lead to gallstone formation. One of the causes of their formation is the crystallization of the following substance:
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What method of titrimetric analysis can be applied for the quantitative determination of sulphuric acid by means of the potassium hydroxide solution?
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Ions of which chemical element have an impact on the electrolytic balance of cerebral tissues. What salt of this element is used for treating the psychic disorders?
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Drug production commonly involves the processes of adsorption and ion exchange. What ion is selectively adsorbed from the aqueous solution based on silver chloride crystal?
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Osmotic pressure is an important characteristic of biologic fluids. Osmotic pressure variates with time in the following solution:
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3-aminopropane acid is included in pantothenic acid which is a component of coenzyme
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The given reaction is called: {# "img":"0h1bd3xczlm4ixwv8egsir15g.png", "alt":"Option","whb":"307:183:" #}
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