A 20-year-old patient complains of general weakness, fever, headache. These presentations appeared three days ago. Objectively: the regional lymph nodes are enlarged, painful on palpationl, body temperature is 37,8°C, oral mucosa is hyperemic and edematous. Mucous mebrane of lips, palate, gums, cheeks presents single erosions of polycyclic irregular shape, covered with grayish-white film, painful. Which drugs should be administered for the local treatment of the early disease?