A 28-year-old patient has been admitted to the oral and maxillofacial surgery for a carbuncle of face. Objectively: the patient is in a critical condition, face, mucous membranes of lips and conjunctiva are edematous and cyanotic. Body temperature is 40°C. The patient presents with delirium, hallucinations. The carbuncle is located on the upper lip, the surrounding soft tissues are swollen. Palpebral fissures are closed due to the edema of eyelids. What is the most likely complication of carbuncle?