A 52-year-old woman suffering from obesity, complains of bloody discharges from genital tracts during 4 days. Last normal menses were 2 years ago. Histological investigation of biopsy of the endometrium has revealed adenomatous hyperplasia. What reason from the mentioned below caused the development of disease?

Answer options

1. Poor aromatization of preandrogens due to hypothyroidism
2. Supersecretion of androgens by the cortex of paranephroses
3. Excessive transformation of preandrogens from adipose tissues
4. Hypersecretion of estrogens by tissues of the organism
5. The increased contents of follicle-stimulating hormone

Explanation

A 52-year-old woman suffering from obesity complains of bloody discharges from sexual paths during 4 days. Last normal menses were 2 years ago. Histological investigation of biopsy of the endometrium has revealed adenomatous hyperplasia. What reason from the mentioned below caused the development of disease?