A 52 y.o. hard smoker patient complains of persistent cough with purulent sputum discharge especially in mornings, dyspnea provoked even by slight physi- cal exertion, wheezing chest, tahypnoe, general weakness. He considers himself to be ill during 12 years. The overwritten conditions appear 3-4 times per year usually after common cold and have tendency to progress. What disease do you think about first of all?