A 35 y.o. woman is suspected of aplastic anemia. The bone marrow puncti-on has been administered with the diagnostic purpose. What changes in the marrow punctatum are suggested?

Answer options

1. Absolute lymphocytosis
2. Replacement of marrow elements with adipose tissue
3. Presence of blast cells
4. Prevalence of megaloblasts
5. Replacement of marrow elements with fibrous tissue