A 32-year-old patient complains about pain in small joints of her hands, paresthesia at the tips of fingers, weakness, difficult deglutition. She has been suffering from this for 13 years. Objectively: face amimia, shortening of nail bones, skin indurations in the area of shoulder girdle are present. Roentgenological examination of lungs revealed basal pneumosclerosis. Fibrogastroscopy revealed esophagus constriction in its cardial part. Blood count: leukocytes - 9,8 × 109/l, ESR - 22 mm/h, y-globulin - 22%. What is the most probable diagnosis?

Answer options

1. Rheumatoid arthritis
2. Systemic scleroderma
3. Systemic lupus erythematosus
4. Dermatomyositis
5. Myxedema

Explanation

A 32 year old patient complains about pain in small joints of her hands, paresthesia at the tips of fingers, weakness, difficult diglutition. She has been suffering from this for 13 years. Objectively: face amimia, shortening of nail bones, skin indurations in the area of shoulder girdle are present. Roentgenological examination of lungs revealed basal pneumosclerosis. Fibrogastroscopy revealed esophagus constriction in its cardial part. Blood count: leukocytes - 9, 8 · 109/l, ESR – 22 mm/h, γ-globulin - 22%.What is the most probable diagnosis?Systemic scleroderma, also called diffuse scleroderma or systemic sclerosis, is an autoimmune disease of the connective tissue. It is characterized by thickening of the skin caused by accumulation of collagen, and by injuries to small arteries.