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Exam questionKROK 2Medicine ยท 2008

A 32-year-old patient complains about heartburn and dull pain in the epigastrium that appear 2-3 hours after meal. Exacerbations happen in spring and in autumn. The patient has food intolerance of eggs and fish. Objectively: stomach palpation reveals painfulness in the gastroduodenal area. Electrophasoduodenoscopy revealed a 5 mm ulcer on the anterior wall of duodenum. Urease test is positive. What is the most probable leading mechanism of disease development?

Answer options

  1. Reduced prostaglandin synthesis
  2. Disorder of gastric motor activity
  3. Autoantibody production
  4. Chelicobacterial infection
  5. Dietary allergy
Correct answer

Chelicobacterial infection

Explanation

A 32 year old patient complains about heartburn and dull pain in the epigastrium that appear 2-3 hours after meal. Exacerbations happen in spring and in autumn. The patient has food intolerance of eggs and fish. Objectively: stomach palpation reveals painfulness in the gastroduodenal area. Electrophasoduodenoscopy revealed a 5 mm ulcer on the anterior wall of duodenum. Urease test is positive. What is the most probable leading mechanism of disease development?Urease test positive revelers Heliobacteria infection.

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