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Exam questionKROK 2Medicine ยท 2010

A 27-year-old patient with malaria caused by P. falciparum was treated with Chloroquine (600 mg base followed by 300 mg base in 6 hours, then 300 mg base a day for 2 days) without clinical and parasitologic responses to the treatment. What is the most likely reason for the failure to respond to the therapy?

Answer options

  1. Inappropriate route of administration
  2. Glucose-6-phosphate dehydrogenase deficiency in patient
  3. Chloroquine resistant strain of P. falciparum
  4. Late recognition of infection due to P. falciparum
  5. Hypersensitivity of the patient to Chloroquine
Correct answer

Chloroquine resistant strain of P. falciparum

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