A 42-year-old patient complains of back pain, darkened urine, general weakness, dizziness that occurred after treating a cold with aspirin and ampicillin. Objectively: the patient is pale, with subicteric sclerae. HR - 98 bpm. Liver - 2 cm, spleen - 3 cm. In blood: RBCs - 2,6 × 1012/l, Hb - 60 g/l, CI - 0,9, WBCs -9,4 × 109/l, basophils - 0,5%, eosinophils - 3%, stab neutrophils - 6% segmented neutrophils - 58%, lymphocytes - 25%, monocytes - 7%, ESR - 38 mm/hour, reticulocytes - 24%. Total bilirubin - 38 millimole/l. What complication occurred in the patient?

Answer options

1. Agranulocytosis
2. Cholelithiasis
3. Acquired hemolytic anemia
4. Paroxysmal nocturnal hemoglobinuria
5. Toxic hepatitis

Explanation

A 42-year-old patient complains of back pain, darkened urine, general weakness, dizziness that occurred after treating a cold with aspirin and ampicillin. Objectively: the patient is pale, with subicteric sclerae. HR - 98 bpm. Liver - 2 cm, spleen - 3 cm. In blood: RBCs - 2,6 • 1012/l, Hb - 60 g/l, CI - 0,9, WBCs -9,4 • 109/l, basophils - 0,5%, eosinophils - 3%, stab neutrophils - 6% segmented neutrophils - 58%, lymphocytes - 25%, monocytes - 7%, ESR - 38 mm/hour, reticulocytes - 24%. Total bilirubin - 38 milli-mole/l. What complication occurred in the patient?