A 49-year-old patient complains of deglutition problems, especially with solid food, hiccups, voice hoarseness, nausea, regurgitation, significant weight loss (15 kg within 2,5 months). Objectively: body weight is reduced. Skin is pale and dry. In lungs: vesicular breathing, heart sounds are loud enough, heart activity is rhythmic. The abdomen is soft, painless on palpation. Liver is not enlarged. What study is required to make a diagnosis?

Answer options

1. X-ray of digestive tract organs
2. Clinical blood test
3. X-ray in Trendelenburg’s position
4. Esophageal duodenoscopy along with biopsy
5. Study of gastric secretion

Explanation

A 49-year-old patient complains of deglutition problems, especially with solid food, hiccups, voice hoarseness, nausea, regurgitation, significant weight loss (15 kg within 2,5 months). Objectively: body weight is reduced. Skin is pale and dry. In lungs: vesicular breathing, heart sounds are loud enough, heart activity is rhythmic. The abdomen is soft, painless on palpation. Liver is not enlarged. What study is required to make a diagnosis? There is the loss of weight, deglutition problem with solid food thus, the patient is suspected to have cancer and the best method of investigation, in this case, is Esophagogastroduodenoscopy with biopsy.