A patient complains of retrosternal pain, difficult swallowing, over 10 kg weight loss within three months, general weakness. In blood: hypochromic anaemia, neutrophilic leukocytosis. In feces: weakly positive Gregersen's reaction. On esophagram a filling defect with ill-defined serrated edges shows up along a large portion of the esophagus. What is the most likely diagnosis?

Answer options

1. Esophageal carcinoma
2. Peptic ulcer
3. Esophageal achalasia
4. Benign tumour
5. Sideropenic dysphagia

Explanation

A patient complains of retrosternal pain, difficult swallowing, over 10 kg weight loss within three months, general weakness. In blood: hypochromic anaemia, neutrophilic leukocytosis. In feces: weakly positive Gregersen's reaction. On esophagram a filling defect with ill-defined serrated edges shows up along a large portion of the esophagus. What is the most likely diagnosis? Sudden weight loss is an alarm sign of cancer and the patient has difficulty in swallowing, esophageal shows an ill-defined edge indicate esophageal cancer.