A 68-year-old patient complains of pain, slight swelling and creaking in the distal joints of her fingers and knee joints. She has been suffering from this condition for 4 years. Objectively: thickening of knee and interphalangeal joints, restricted mobility of these joints. Blood test: leukocytes -5,4 × 109/l, ESR - 12 mm/h, fibrinogen - 3,5 g/l; Rheumatoid factor -1:32; anti-streptolysin O -160 units; seromucoid - 0,20 units.; CRP+. What mechanism of development is likely for this condition?