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Exam questionKROK 2Medicine · 2019

A 53-year-old man complains of general weakness, loss of appetite, and painful vesicles appearing on his skin. The disease onset occurred suddenly, after hyperinsolation one week ago. Examination detects isolated vesicles with wrinkled opercula and occasional painful erosions on the skin of the patient’s torso and limbs. The Nikolsky sign is positive. What is the most likely diagnosis?

Answer options

  1. Non Acantholytic pemphigus
  2. Acantholytic pemphigus
  3. Herpes
  4. Duhring’s disease (dermatitis herpetiformis)
  5. Toxicodermia
Correct answer

Acantholytic pemphigus

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