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Exam questionKROK 2Medicine · 2020

A 56-year-old man presents for a checkup. The patient says he has to urinate quite frequently, but denies any dysuria or pain on urination. Past medical history is significant for diabetes mellitus type 2 and hypertension, both managed medically. Current medications are metformin, aspirin, rosuvastatin, captopril and furosemide. Laboratory findings are significant for the following: Glycated Hemoglobin (Hb A1c) - 8.0%, Fasting Blood Glucose - 12 mmol/L. His doctor decides to add glibenclamide to the therapy. Which of the following is the most likely mechanism of this drug’s action?

Answer options

  1. Stimulation of insulin release
  2. Inhibition of insulin release
  3. Stimulation of glucose reuptake by the cell
  4. -
  5. Facilitation of glucose absorption in the intestine
Correct answer

Stimulation of insulin release

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