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Exam questionKROK 2Medicine · 2020

A 38-year-old woman, who was diagnosed with systemic lupus erythematosus (SLE) 3 years ago, comes to her physician with a complaint of facial swelling and decreased urination that she first noticed 2 weeks ago. She currently takes azathioprine and corticosteroid. Her vital signs show blood pressure 150/90 mm Hg, pulse - 91/min., temperature - 36.8°C and respiratory rate - 15/min. On physical examination, the doctor notices erythematous rash on her face exhibiting a butterfly pattern. The laboratory studies reveal hypercholesterolemia, hypertriglyceridemia and proteinuria. Which of the following is the most likely mechanism of SLE’s complication in this patient?

Answer options

  1. Decrease in renal blood flow (ischemic nephropathy)
  2. Acute infection of the kidney
  3. Increased plasma oncotic pressure
  4. -
  5. Immune complex-mediated glomerular disease
Correct answer

Immune complex-mediated glomerular disease

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