A 22-year-old woman with suspected systemic lupus erythematosus complains of "flying" pain in the joints of the arms and legs, fever up to 38.5-39°C for 3 weeks, shortness of breath,palpitations, weakness. Objectively established: erythema on the cheeks and nose. In the blood found: Hb - 90 g/l, platelets - 135 × 10 ^ g/l, ESR - 43 mm/h. In the urine found: protein - 2.66 g/l, erythrocytes - 8-10 in p/s. Detection of which antibodies in patients is most important for diagnosis?