A 55-year-old woman complains of a tumor-like formation that can be palpated in the kidney area on the left, moderate dull in her left side, periodical discharge of right-red blood during urination. Objectively, the patient has lost weight, her skin is pale and dry. Palpation of the abdomen detects an clastic formation in the left renal region. The formation is mobile and painless. Urinalysis detects macrohematuria and atypical cells. Blood Hb is 82 g/L, ESR is 70mm/hour. What is the most likely pathology, causing this clinical presentation?