Exam questionKROK 2Pharmacy · 2013
A patient suffering from epilepsy has taken phenobarbital for a long time and developed drug tolerance. What is the mechanism of this phenomenon development?
Answer options
- Inhibition of biotransformation
- Absorption process reduction
- Acceleration of biotransformation
- Accumulation of substances in the body
- Receptor’s sensitivity enhancement
Correct answer
Acceleration of biotransformation
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