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Exam questionKROK 1Dentistry ยท 2019

During a class in molecular biology the mutations resulting in production of abnormal haemoglobin are being studied. What amino acid substitution occurs when S-haemoglobin is being produced, resulting in the development of sickle cell anemia?

Answer options

  1. Glycine is substituted with asparagine
  2. Glutamic acid substituted with valine
  3. Threonine is substituted with lysine
  4. Lysine is substituted with glutamine
  5. Histidine is substituted with arginine
Correct answer

Glutamic acid substituted with valine

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