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Exam questionKROK 1Medicine ยท 2011

Researchers isolated 5 isoenzymic forms of lactate dehydrogenase from the human blood serum and studied their properties. What property indicates that the isoenzymic forms were isolated from the same enzyme?

Answer options

  1. The same molecular weight
  2. The same electrophoretic mobility
  3. Tissue localization
  4. Catalyzation of the same reaction
  5. The same physicochemical properties
Correct answer

Catalyzation of the same reaction

Explanation

Isozymes, also known as isoenzymes are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. The existence of isozymes permits the fine-tuning of metabolism to meet the particular needs of a given tissue or developmental stage (for example lactate dehydrogenase (LDH)).

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