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KROK 1 Medicine 2011 Questions | KROKEXAM

Browse 2011 KROK 1 Medicine exam questions with answers and explanations.

Exam questions

200 Questions
1

A 30-year-old patient complains about having abdominal pain and diarrhea for five days; body temperature rise up to 37,5°C along with chills. The day before a patient had been in a forest and drunk from an open water reservoir. Laboratory analyzes enabled to make the following diagnosis: amebic dysentery. What is the drug of choice for its treatment?

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2

Quite often the cause of secondary immunodeficiency is an infection involvement, when the causative agents propagate directly in the cells of immune system and destroy it. The following diseases are characterized by:

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3

Heart rate of a 30-year-old man under emotional stress reached 112 bpm. The reason for the heart rate increase is the altered condition of the following conducting system of heart:

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4

Sanitary bacteriological research on water by the membrane filter method revealed two red colonies on a membrane filter (Endo agar) through which 500 ml of analyzed water were passed. Calculate the coli index and coli titer of the analyzed water:

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5

A 46-year-old female patient has a continuous history of progressive muscular (Duchenne's) dystrophy. Which blood enzyme changes will be of diagnostic value in this case?

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6

Extensive thromboembolic infarction of the left cerebral hemispheres, large septic spleen, immunocomplex glomerulonephritis, ulcers on the edges of the aortic valves, covered with polypous thrombus with colonies of staphylococcus were revealed on autopsy of the young man who died in coma. What disease caused cerebral thromboemboly?

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7

A 10-year-old girl has a history of repeated acute respiratory viral infection. After recovering she presents with multiple petechial hemorrhages on the sites of friction from clothing rubbing the skin. What kind of hypovitaminosis has this girl?

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8

Autopsy of a patient who suffered from croupous pneumonia and died from pneumococcal sepsis revealed 900 ml of turbid greenish-yellow liquid in the right pleural cavity. Pleural leaves are dull, plephoric. Name the clinicopathological form of inflammation in the pleural cavity:

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9

Researchers isolated 5 isoenzymic forms of lactate dehydrogenase from the human blood serum and studied their properties. What property indicates that the isoenzymic forms were isolated from the same enzyme?

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10

A patient suffering from stomach ulcer has been treated with an antacid drug almagel. For acute bronchitis treatment he was prescribed the antibiotic methacycline. However within next 5 days the fever didn’t fall, cough and sputum nature remained unchanged. A physician came to the conclusion that the drugs were incompatible. What type of drug incompatibility is the case?

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11

ECG of a 44-year-old patient shows signs of hypertrophy of both ventricles and the right atrium. The patient was diagnosed with the tricuspid valve insufficiency. What pathogenetic variant of cardiac dysfunction is usually observed in case of such insufficiency?

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12

Proserin increases skeletal muscle tone when given systematically. Halothane induces relaxation of skeletal muscles and reduces proserin effects. What is the nature of proserin and halothane interaction?

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13

The minute blood volume in a patient with transplanted heart has increased as a result of physical activity. What regulative mechanism is responsible for these changes?

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14

An aged man had raise of arterial pressure under a stress. It was caused by activation of:

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15

Autopsy of a man who died from chronic cardiovascular collapse revealed "tiger heart". Sidewards of endocardium a yellowish-white banding can be seen; myocardium is dull, dark-yellow. What process caused this pathology?

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16

A 55-year-old male patient was hospitalized to a surgical clinic for suspected septicemia. What material should be taken for analysis?

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17

A patient has pellagra. Interrogation revealed that he had lived mostly on maize for a long time and eaten little meat. This disease had been caused by the deficit of the following substance in the maize:

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18

During examination of a 6-year-old child a doctor revealed greyish films on the pharyngeal tonsils. Their removal provoked moderate hemorrhage. Bacterioscopy revealed gram-positive clublike bacteria. What symptoms will develop in this child within the next few days if no specific treatment is provided?

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19

A 46-year-old patient consulted a doctor complaining about joint pain that becomes stronger the day before the weather changes. Blood examination revealed an increased concentration of uric acid. The most probable cause of the disease is the intensified disintegration of the following substance:

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20

12 hours after an accute attack of retrosternal pain a patient presented a jump of aspartate aminotransferase activity in blood serum. What pathology is this deviation typical for?

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21

After a trauma of the upper third of the anterior forearm surface a patient presents with difficult pronation, weakening of palmar flexor muscles and altered skin sensitivity of 1-3 fingers. Which nerve is damaged?

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22

A 2-year-old child with mental and physical retardation has been delivered to a hospital. He presents with frequent vomiting after having meals. There is phenylpyruvic acid in urine. Which metabolism abnormality is the reason for this pathology?

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23

A 38-year-old man died in the attempt of lifting weight. He had collaptoid state. Autopsy revealed an extensive aneurism rupture of thoracic aorta. He suffered from visceral syphilis during his lifetime. What pathological process caused weakness of aortic wall, its dilatation and rupture?

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24

A patient suffering from myasthenia has been administered proserin. After its administration the patient has got nausea, diarrhea, twitch of tongue and skeletal muscles. What drug would help to eliminate the intoxication?

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25

A man died from an acute infectious disease accompanied by fever, jaundice, haemorrhagic rash on the skin and mucous membranes as well as by acute renal insufficiency. Histological examination of renal tissue (stained by Romanovsky-Giemsa method) revealed some convoluted bacteria looking like C und S letters. What bacteria were revealed?

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26

A 46-year-old patient suffering from the diffuse toxic goiter underwent resection of the thyroid gland. After the surgery the patient presents with appetite loss, dyspepsia, increased neuromuscular excitement. The body weight remained unchanged. Body temperature is normal. Which of the following has caused such a condition in this patient?

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27

Medical examination at the military registration and enlistment office revealed that a 15-year-old boy was high, with eunuchoid body proportions, gynecomastia, female pattern of pubic hair distribution. The boy had also fat deposits on the thighs, no facial hair, high voice, subnormal intelligence quotient. Which karyotype corresponds with this disease?

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28

A doctor recommends a patient with duodenal ulcer to drink cabbage and potato juice after the therapy course. Which substances contained in these vegetables help to heal and prevent the ulcers?

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29

Urine analysis of a 12-year-old boy reveals high concentration of all aliphatic amino acids with the highest excretion of cystine and cysteine. US of kidneys revealed kidney concrements. What is the most likely pathology?

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30

A 5-year-old child has been diagnosed with acute right distal pneumonia. Sputum inoculation revealed that the causative agent is resistant to penicillin, but it is senstive to macrolides. What drug should be prescribed?

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31

Autopsy of a 73-year-old man who had been suffering from the coronary heart disease along with cardiac insufficiency for a long time revealed: nutmeg liver, brown induration of lungs, cyanotic induration of kidneys and spleen. What kind of circulation disorder was the cause of such effects?

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32

A patient suffering from chronic hyperacidic gastritis takes an antacid drug for heartburn elimination. After its ingestion the patient feels better but at the same time he has a sensation of stomach swelling. Which of the following drugs might be the cause of such side effect?

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33

A 30-year-old male patient with acute pancreatitis has been found to have a disorder of cavitary protein digestion. The reason for such condition can be the hyposynthesis and hyposecretion of the following enzyme:

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34

A patient has been given high doses of hydrocortisone for a long time. This caused atrophy of one of the adrenal cortex zones. Which zone is it?

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35

A victim of an accident has bleeding from the soft tissues anteriad the mandibular angle. Which vessel should be ligated for the bleeding arrest?

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36

Microscopic examination of a gram-stained scrape from a patient's tongue revealed oval, round, elongated chains of dark-violet gemmating cells. What disease can be caused by this causative agent?

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37

The greater amount of nitrogen is excreted from the organism in form of urea. Inhibition of urea synthesis and accumulation of ammonia in blood and tissues are induced by the decreased activity of the following liver enzyme:

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38

A 36-year-old female patient has a history of collagen disease. Urine analysis is likely to reveal an increased concentration of the following metabolite:

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39

A coprological survey revealed light-colored feces containing drops of neutral fat. The most likely reason for this condition is the disorder of:

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40

The secretion of whixh hypophysial hormones will be inhibited after taking the oral contraceptives containing sex hormones?

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