When examining a biopsy material obtained from the thyroid gland, the pathologist discovered lymphocyte infiltration of the thyroid tissues and destruction of the parenchymal elements. Diffuse lymphocyte infiltration with lymphoid follicles was detected in the stroma. What is the most likely diagnosis?

Answer options

1. Undifferentiated thyroid carcinoma
2. Solid adenoma of the thyroid
3. Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis)
4. Papillary thyroid cancer
5. Graves’ disease (toxic diffuse goiter)

Explanation

When examining a biopsy material obtained from the thyroid gland, the pathologist discovered lymphocyte infiltration of the thyroid tissues and destruction of the parenchymal elements. Diffuse lymphocyte infiltration with lymphoid follicles was detected in the stroma. What is the most likely diagnosis?Hashimoto's thyroiditis (chronic lymphocytic thyroiditis). Hashimoto disease is an autoimmune hypothyroidism disease in which the thyroid gland is gradually destroyed.