Exam questionKROK 1Medicine · 2018
A 40-year-old woman suffers from Cushing’s disease – steroid diabetes. On biochemical examination she has hyperglycemia and hypochloremia. What process activates in the first place in such patients?
Answer options
- Glycolysis
- Glycogenolysis
- Glucose reabsorption
- Glucose transport to the cells
- Gluconeogenesis
Correct answer
Gluconeogenesis
Explanation
Gluconeogenesis is a metabolic pathway that results in the generation of glucose from noncarbohydrate carbon substrates Cushing's disease is used exclusively to describe the condition of excessive cortisol arising from a pituitary tumor secreting the hormone ACTH. Hyperglycemia BECAUSE cortisol is gluconeogenic.It should be noted that exogenous causes of
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