On examination the patient presents with hirsutism, moon-shaped face, stretch marks on the abdomen. BP is 190/100 mm Hg, blood glucose is 17.6 mmol/L. What pathology is such clinical presentation characteristic of?

Answer options

1. Adrenocortical hyperfunction
2. Gonadal hypofunction
3. Hyperfunction of the insular apparatus
4. Hyperthyroidism
5. Hypothyroidism

Explanation

Cushing's Disease: Adrenal Cortex Hyper production due to Pituitary Adenoma leads to a high level of ACTH, thus causes Hirsutism, Abdominal Stretch Mark, Moon Shaped Face, Upper body obesity, and Hypertension. Cushing's Syndrome: High level of Cortisol, without Pituitary Tumor.