Various biological preparations can be used for poliomyelitis prevention. What drug induces the type of local intestinal mucosal immunity that lasts the longest?

Answer options

1. Parenteral vaccination with live vaccine
2. Oral introduction of poliovirus-specific immunoglobulin
3. Parenteral introduction of normal human immunoglobulin
4. Parenteral vaccination with inactivated vaccine
5. Oral vaccination with live vaccine

Explanation

For poliomyelitis prevention, oral vaccines with live vaccines are used so that secretory IgA antibodies can induce local intestinal mucosal immunity which lasts for a longer time.