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Exam questionKROK 1Medicine ยท 2021

A patient with microspherocytic hemolytic anemia (Minkowski-Chaufland disease) presents with increased permeability of erythrocyte membrane, which causes increased entry of sodium ions and water into the cell. As a result, erythrocytes assume the shape of spherocytes and can be easily destroyed. What is the leading mechanism of erythrocyte damage in this case?

Answer options

  1. Acidotic
  2. Electrolytc-osmotic
  3. protein
  4. Nucleic
  5. Calcium
Correct answer

Electrolytc-osmotic

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