In hepatitis and myocardial infarction, the activity of alanine and aspartate aminotransferases sharply increases in the patients' blood plasma. Why does this Increase in the activity of these enzymes in the blood occur?

Answer options

1. Amino acid synthesis acceleration in tissues
2. Pyridoxine deficiency
3. Damage to cell membranes and release of enzymes into the blood
4. Hormone-induced increase in enzyme activity
5. Amino acid breakdown acceleration in tissues