A 38-year-old woman, who was diagnosed with systemic lupus erythematosus (SLE) 3 years ago, came to her physician with a complaint of facial swelling and decreased urination that she first noticed 2 weeks ago. She currently takes azathio rine and corticosteroid. Her vital signs s ow blood pressure 150/90 mm Hg, pulse — 91/min., temperature — 36.80C and respiratory rate — 15/min. On physical examination, the doctor notices erythematous rash on her face exhibiting a butterfly pattern. The laboratory studies reveal hypercholesterolemia, hypertriglyceridemia, and proteinuria. The most likely mechanism of SLE's complication in this patient is: