In an experiment, a neuromuscular preparation of frog was treated with a curare-like substance. As a result, muscle contractions in response to electrical stimulation of the nerve disappeared. What function of the muscle cell membrane is disrupted by curare-like drugs?

Answer options

1. Creation of electric potentials on the both sides of the membrane
2. Maintenance of different permeability for different substances
3. Creating a barrier between the intracellular environment and surrounding intercellular fluid
4. Reception of mediators in the neuromuscular synapse
5. Maintenance of the internal cellular structure, its cytoskeleton