Exam questionKROK 2Pharmacy ยท 2010
On the 4th day of treatment with indometacin a 55-year-old patient developed gastrorrhagia as a result of gastric mucosa ulcer. Ulcerogenic effect of this drug is explained by the lowered activity of the following enzyme:
Answer options
- Cyclooxygenase-1 (COX -1)
- Thromboxanetin sintetaza
- Cyclooxygenase-2 (COX -2)
- Prostacyclin sintetaza
- Lipoxygenase (LOG)
Correct answer
Cyclooxygenase-1 (COX -1)
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