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Exam questionKROK 2Pharmacy ยท 2012

On the 4th day of treatment with indomethacin a 55-year-old patient developed gastric bleeding as a result of ulceration of the gastric mucosa. Ulcerogenic effect of this drug is due to a decrease in activity of the following enzyme:

Answer options

  1. Cyclooxygenase-2 (COX-2)
  2. Lipoxygenase (LOX)
  3. Thromboxane synthetase
  4. Cyclooxygenase-1 (COX-1)
  5. Prostacyclin synthetase
Correct answer

Cyclooxygenase-1 (COX-1)

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